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Classification of AKI by serum creatinine (AKIN)
- Stage I - 150% increase in serum creatinine
- Stage II - 200% increase in serum creatinine
- Stage III - 300+% increase in serum creatinine
Classification of AKI by urine output
- Stage I - <0.5mL/kg/h for 6-12 hours
- Stage II - <0.5mL/kg/h for more than 12 hours
- Stage III - <0.3mL/kg/h for at least 24 hours OR anuria for more than 12 hours
The usual culprits
- Pre-renal: hypotension/hypoperfusion from any cause (sepsis, hypovolaemia, shock, NSAID…)
- Renal/intrinsic: AIN, ATN, other weird and wonderful nephropathies
- Post-renal: obstruction (of the renal tract, or the renal vein)
Further reading
- Find your own